- Safety data derived from Xerese clinical studies reflect exposure to Xerese in 1056 subjects with recurrent herpes labialis who were treated 5 times daily for 5 days
- Most common adverse reactions (<1%) were local skin reactions and occurred in the area of application
- Most common adverse reactions included:
- Drying or flaking of the skin
- Burning or tingling following application
- Pigmentation changes
- Application site reactions, including signs and symptoms of inflammation
- No photoallergic or phototoxicity potential was identified for XERESE in 2 studies involving 50 and 30 healthy volunteers, respectively
Xerese is intended for cutaneous use only for herpes labialis of the lips and around the mouth.
There are other orofacial lesions, including bacterial and fungal infections, which may be difficult to distinguish from a cold sore. Encourage patients to seek medical advice when a cold sore fails to heal within 2 weeks.
Xerese has a potential for irritation and contact sensitization.