Safety Profile

Safety Profile
  • Safety data derived from Xerese clinical studies reflect exposure to Xerese in 1056 subjects with recurrent herpes labialis who were treated 5 times daily for 5 days
  • Most common adverse reactions (<1%) were local skin reactions and occurred in the area of application
  • Most common adverse reactions included:
    • Drying or flaking of the skin
    • Burning or tingling following application
    • Erythema
    • Pigmentation changes
    • Application site reactions, including signs and symptoms of inflammation
  • No photoallergic or phototoxicity potential was identified for XERESE in 2 studies involving 50 and 30 healthy volunteers, respectively

Xerese is intended for cutaneous use only for herpes labialis of the lips and around the mouth.

There are other orofacial lesions, including bacterial and fungal infections, which may be difficult to distinguish from a cold sore. Encourage patients to seek medical advice when a cold sore fails to heal within 2 weeks.

Xerese has a potential for irritation and contact sensitization.

What makes Xerese different, Learn about its dual action
Instant Savings Offer
1. XERESE® (acyclovir and hydrocortisone) cream 5%/1% Prescribing Information. January, 2014.

*This offer is only valid for patients with commercial insurance. Eligible uninsured patients will pay more. This offer is not valid for any person eligible for reimbursement of prescriptions, in whole or in part, by any federal, state, or other governmental programs, including, but not limited to, Medicare (including Medicare Advantage and Part A, B, and D plans), Medicaid, TRICARE, Veterans Administration or Department of Defense health coverage, CHAMPUS, the Puerto Rico Government Health Insurance Plan, or any other federal or state health care programs. This offer is good only in the U.S. at retail pharmacies owned and operated by Walgreen Co. (or its affiliates) or other participating independent retail pharmacies. This offer is not valid in Massachusetts or Minnesota or where otherwise prohibited, taxed or otherwise restricted. Click here for other terms and conditions that apply.